Answer
Famciclovir has not been studied in patients with severe hepatic impairment, but impaired conversion to its active metabolite penciclovir may lower penciclovir plasma concentrations and reduce efficacy.
Sources for this answer
- Famciclovir 250 mg film-coated tabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §4.4 Special warnings and precautions for use · Version 1Document updated
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