Answer
Therapeutic monitoring of CYP450 substrates with a narrow therapeutic index should be considered when epcoritamab is started because transient elevation of certain proinflammatory cytokines may suppress CYP450 enzyme activities.
Sources for this answer
- Tepkinly 4 mg/0.8 ml solution for injectionAbbVie Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 11Document updated
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