Answer
Metreleptin (Myalepta) may alter CYP450 enzymes, potentially affecting narrow-therapeutic-index medicines such as warfarin, so warfarin’s effect should be monitored when metreleptin is started or stopped and its dose adjusted as needed.
Sources for this answer
- Myalepta 3mg powder for solution for injectionChiesi Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 6Document updated
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