Answer
Voriconazole is contraindicated with Efavirenz/Emtricitabine/Tenofovir disoproxil Glenmark because efavirenz significantly decreases voriconazole plasma concentrations, voriconazole significantly increases efavirenz plasma concentrations, and the fixed-dose combination prevents adjustment of the efavirenz dose.
Sources for this answer
- Efavirenz/Emtricitabine/Tenofovir disoproxil Glenmark 600 mg/ 200 mg/245 mg film-coated tabletsGlenmark Pharmaceuticals Europe Ltd · emc · SmPC §4.3 Contraindications · Version 5Document updated
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