Answer
Using canakinumab with TNF inhibitors is not recommended because it may increase serious infection risk, as an increased incidence of serious infections has been associated with another IL-1 blocker combined with TNF inhibitors.
Sources for this answer
- Ilaris 150mg/ml Solution for InjectionNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 8Document updated
Sources checked