Why is thiotepa contraindicated during pregnancy?

Name: Why is thiotepa contraindicated during pregnancy?
Published: 2026-11-08T02:03:30.678Z

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Thiotepa is contraindicated during pregnancy because preclinical studies showed embryofoetal death and birth defects, and there are no data on its use during human pregnancy.

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Thiotepa Riemser 15 mg powder for concentrate for solution for infusionEsteve Pharmaceuticals (formerly Intrapharm Laboratories) · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 2Document updated 27 September 2023

Sources checked 8 November 2026

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