Answer
Taking simvastatin with lopinavir + ritonavir is contraindicated because it increases simvastatin plasma concentrations, raising the risk of myopathy, including rhabdomyolysis.
Sources for this answer
- Kaletra 80mg/20mg Oral Solution (Great Britain)AbbVie Ltd · emc · SmPC §4.3 Contraindications · Version 60Document updated
Sources checked