Answer
Taking mavacamten with rifampicin is not recommended because rifampicin strongly induces both CYP2C19 and CYP3A4, which is expected to significantly alter mavacamten pharmacokinetics and reduce its efficacy.
Sources for this answer
- Mavacamten BMS 2.5 mg, 5 mg, 10 mg, 15 mg hard capsulesBristol Myers Squibb Pharmaceuticals limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 6Document updated
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