Answer
Digoxin lowers heart rate, and taking it when starting ponesimod may cause severe bradycardia and heart block, so cardiologist advice should be obtained before initiation to assess risks, monitoring and a possible switch to a medicine that does not lower heart rate.
Sources for this answer
- Ponvory 20 mg film-coated tabletsLaboratoires Juvise Pharmaceuticals · emc · SmPC §4.4 Special warnings and precautions for use · Version 3Document updated
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