Answer
Taking alprazolam with ketoconazole or itraconazole is not recommended because inhibition of hepatic enzymes, particularly CYP3A4, may increase alprazolam concentrations and enhance its activity.
Sources for this answer
- Xanax 500 microgram TabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §4.5 Interaction with other medicinal products · Version 25Document updated
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