Answer
Radium-223 dichloride (Xofigo) is contraindicated with abiraterone acetate and prednisone or prednisolone because a clinical study found increased fracture risk and a trend towards increased mortality compared with placebo plus abiraterone acetate and prednisone or prednisolone.
Sources for this answer
- Xofigo 1100 kBq/mL solution for injectionBayer plc · emc · SmPC §4.4 Special warnings and precautions for use · Version 11Document updated
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