Answer
Opium tincture (Dropizol) is contraindicated during breastfeeding because opium enters breast milk, and maternal CYP2D6 ultra-rapid metabolism can increase milk morphine levels, very rarely causing potentially fatal opioid toxicity in the infant.
Sources for this answer
- Dropizol 10mg/ml oral dropsPharmanovia A/S · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 4Document updated
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