opicapone · Medicine question

Why is opicapone contraindicated with phenelzine?

iatroX medicinesPublished 8 November 2026

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Opicapone is contraindicated with phenelzine because combining opicapone with this MAO inhibitor could inhibit the majority of pathways responsible for catecholamine metabolism.

Sources for this answer

Ongentys 50 mg hard capsulesBial Pharma UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 7Document updated 8 July 2025

Sources checked 8 November 2026

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