Why is Nuromol Dual Action (ibuprofen + paracetamol) contraindicated during the third trimester of pregnancy?

Nuromol Dual Action is contraindicated in the third trimester because prostaglandin inhibition may cause fetal cardiopulmonary toxicity (premature ductus arteriosus constriction/closure and pulmonary hypertension), renal dysfunction, prolonged bleeding in mother and newborn, and inhibited uterine contractions causing delayed or prolonged labour.