Answer
Monitoring digoxin’s clinical effects is recommended with Tepmetko because tepotinib can inhibit transport of sensitive P-gp substrates, and digoxin is a P-gp-dependent medicine with a narrow therapeutic index.
Sources for this answer
- TEPMETKO 225 mg film-coated tabletsMerck · emc · SmPC §4.5 Interaction with other medicinal products · Version 7Document updated
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