Answer
Blocking the renin–angiotensin system can alter kidney filtration, particularly with renal artery narrowing, dehydration, kidney disease or interacting medicines.
Sources for this answer
- Irbesartan 75 mg tablets — Current selected SmPCemc · Summary of Product Characteristics
- NHS Specialist Pharmacy ServiceNHS Specialist Pharmacy Service · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.