Answer
Most ganciclovir is removed unchanged by the kidneys. Reduced kidney function increases exposure and toxicity risk.
Sources for this answer
- Ganciclovir 500mg powder for Solution for Infusion vial — Current selected SmPCemc · Summary of Product Characteristics
- Cymevene_500mg_powder-for-concentrate-for-solution-for-infusion — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.