Answer
Ketoconazole is contraindicated with isavuconazonium sulfate (Cresemba) because its strong CYP3A4/5 inhibition can significantly increase plasma concentrations of isavuconazole.
Sources for this answer
- CRESEMBA 200mg Powder for concentrate for solution for infusionPfizer Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 22Document updated
Sources checked