Answer
INR monitoring is recommended when warfarin is taken with Symkevi in combination with ivacaftor because ivacaftor may inhibit CYP2C9.
Sources for this answer
- Symkevi 100 mg/150 mg tablets PLGB 22352/0003Vertex Pharmaceuticals (Europe) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 14Document updated
Sources checked