Answer
It can trigger a faster heartbeat and fluid retention. A beta-blocker or another sympatholytic may limit the faster heartbeat, while a diuretic may reduce fluid retention. Nitrates are part of its licensed combination role in selected heart failure.
Sources for this answer
- Hydralazine 25 mg Tablets / Apresoline 25 mg Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.