Answer
Rasburicase produces hydrogen peroxide while breaking down uric acid. In G6PD deficiency this can cause dangerous red-cell breakdown, so rasburicase is contraindicated.
Sources for this answer
- Fasturtec 1.5 mg/ml powder and solvent for concentrate for solution for infusion — Current selected SmPCemc · Summary of Product Characteristics
- NHS Specialist Pharmacy ServiceNHS Specialist Pharmacy Service · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.