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Medicines folinic acidQuestion & answer

folinic acid · Medicine question

Why is folinic acid combined with fluorouracil?

iatroX medicinesPublished 20 August 2026Reviewed 20 August 2026

The answer

Answer

It prolongs fluorouracil’s inhibition of an enzyme needed for DNA production, increasing anticancer activity but also toxicity.

Sources for this answer

Sodiofolin 50 mg/ml, solution for injectionemc · SmPC Current selected SmPC · Version 13

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The full medicine guide

folinic acid

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