Answer
Fluconazole is contraindicated with Leqselvi (deuruxolitinib phosphate) because its CYP2C9 inhibition is estimated to increase deuruxolitinib exposure, potentially increasing the risk of serious adverse reactions such as thrombosis.
Sources for this answer
- Leqselvi 8 mg film-coated tabletsRanbaxy (UK) Limited a Sun Pharmaceutical Company · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated
Sources checked