Answer
Evinacumab is generally not recommended during pregnancy because human data are limited, animal studies show reproductive toxicity, and it may cross the placenta and harm the foetus, unless the expected benefit to the patient outweighs the potential foetal risk.
Sources for this answer
- Evkeeza 150 mg/ml concentrate for solution for infusionUltragenyx UK · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 4Document updated
Sources checked