erythromycin · Medicine question

Why is erythromycin contraindicated with simvastatin?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Erythromycin is contraindicated with simvastatin because it can increase statin concentrations, and rare cases of rhabdomyolysis have been reported with concurrent use.

Sources for this answer

Erythromycin 250 mg Gastro-resistant TabletsBrown & Burk UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 8Document updated 16 June 2025

Sources checked 8 November 2026

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

Does erythromycin affect the ability to drive or use machines?Does erythromycin pass into breast milk?How does erythromycin act against susceptible bacteria?What are the most frequent side effects of oral erythromycin?What does the evidence say about erythromycin exposure during the first trimester of pregnancy and congenital malformations?What is the association between erythromycin exposure in infancy and infantile hypertrophic pyloric stenosis?

loading page…

Answer

Sources for this answer

More questions about erythromycin

Answer

Sources for this answer

More questions about erythromycin

erythromycin

More clinical questions?