entrectinib · Medicine question

Why is entrectinib not recommended during pregnancy?

iatroX medicinesPublished 8 November 2026

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Entrectinib (Rozlytrek) is not recommended during pregnancy because animal studies and its mechanism of action indicate it may cause foetal harm, and no data are available on its use in pregnant women.

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Rozlytrek 100 mg & 200 mg hard capsulesRoche Products Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 16Document updated 21 May 2026

Sources checked 8 November 2026

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