Answer
Delafloxacin is not recommended in patients with a known history of myasthenia gravis because fluoroquinolones have neuromuscular blocking activity that may worsen muscle weakness, and their use in these patients has been associated with serious reactions, including death and the need for ventilator support.
Sources for this answer
- Quofenix 300 mg powder for concentrate for solution for infusionA. Menarini Farmaceutica Internazionale SRL · emc · SmPC §4.4 Special warnings and precautions for use · Version 9Document updated
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