Answer
Ritonavir slows darunavir’s CYP3A-mediated breakdown, increasing and maintaining its exposure. This product must not be used without its prescribed booster.
Sources for this answer
- Darunavir 600 mg Film-Coated Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.