Answer
Combining pentostatin with high-dose cyclophosphamide is not recommended because acute pulmonary oedema and hypotension leading to death were reported in patients receiving these drugs with carmustine and etoposide as an ablative bone marrow transplant regimen.
Sources for this answer
- Nipent 10 mg powder for solution for injection, powder for solution for infusionHospira UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 10Document updated
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