Answer
Combining azathioprine with febuxostat is not recommended because non-clinical data suggest febuxostat may prolong azathioprine activity, potentially enhancing bone marrow suppression, and data are insufficient to determine an adequate azathioprine dose reduction.
Sources for this answer
- Azathioprine 50mg Film-Coated TabletsTillomed Laboratories Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 9Document updated
Sources checked