Answer
CoAprovel is not recommended during breastfeeding because use information is unavailable, irbesartan’s passage into human milk is unknown, and hydrochlorothiazide enters milk, with high-dose thiazides potentially inhibiting milk production through intense diuresis; alternatives with better-established safety are preferred, especially when nursing newborn or preterm infants.
Sources for this answer
- CoAprovel 300mg/12.5mg TabletsSANOFI · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 18Document updated
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