Answer
Co-administration of Vaborem with probenecid is not recommended because probenecid inhibits meropenem’s renal excretion by competing for active tubular secretion, potentially increasing meropenem concentrations, and the same mechanism could increase vaborbactam concentrations.
Sources for this answer
- Vaborem 1 g/1 g powder for concentrate for solution for infusionA. Menarini Farmaceutica Internazionale SRL · emc · SmPC §4.5 Interaction with other medicinal products · Version 11Document updated
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