Answer
Close viral-load monitoring is recommended during pregnancy with Edurant (rilpivirine hydrochloride) because exposure to rilpivirine 25 mg once daily is lower during pregnancy, and similarly low exposure in phase 3 studies was associated with an increased risk of virological failure.
Sources for this answer
- Edurant 25 mg tablets (Great Britain)Janssen-Cilag Ltd (a Johnson & Johnson Company) · emc · SmPC §4.4 Special warnings and precautions for use · Version 21Document updated
Sources checked