Answer
Chlortalidone is best avoided for hypertension or oedema during pregnancy because diuretic use may be associated with hypovolaemia, increased blood viscosity and reduced placental perfusion, with reports of foetal bone marrow depression, thrombocytopenia, and foetal and neonatal jaundice associated with thiazide diuretics.
Sources for this answer
- Hylaton 50mg TabletsMorningside Healthcare Ltd · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 1Document updated
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