Answer
Caution is recommended because asciminib hydrochloride increases S-warfarin exposure and warfarin is a CYP2C9 substrate with a narrow therapeutic index; no asciminib dose adjustment is required.
Sources for this answer
- Scemblix 20 mg and 40 mg film-coated tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 9Document updated
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