Answer
In adults, caution is needed because ritlecitinib tosylate moderately inhibits CYP1A2, which may increase concentrations of tizanidine, a CYP1A2 substrate, and moderate concentration changes may lead to serious adverse reactions.
Sources for this answer
- Litfulo 50mg hard capsulesPfizer Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 4Document updated
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