sodium nitrite + sodium thiosulfate · Medicine question

Why is caution needed when Nithiodote (sodium nitrite + sodium thiosulfate) is used with procaine or nitroprusside?

Name: Why is caution needed when Nithiodote (sodium nitrite + sodium thiosulfate) is used with procaine or nitroprusside?
Published: 2026-11-08T02:02:55.563Z

iatroX medicinesPublished 8 November 2026

The answer

Answer

Caution is needed because procaine and nitroprusside can also cause methaemoglobinaemia, a risk associated with the sodium nitrite component of Nithiodote.

Sources for this answer

NithiodoteHope Pharmaceuticals Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 2Document updated 15 September 2020

Sources checked 8 November 2026

loading page…

Answer

Sources for this answer

Answer

Sources for this answer

More questions about sodium nitrite + sodium thiosulfate