Answer
Grapefruit juice requires caution during Riamet (artemether + lumefantrine) treatment because administering artemether with grapefruit juice approximately doubled systemic exposure to artemether in healthy adults.
Sources for this answer
- Riamet 20/120mg tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 30Document updated
Sources checked