Answer
Intravenous carmustine is lipid-soluble and crosses the blood–brain barrier. The implant can also release carmustine directly into tissue around the tumour-removal cavity.
Sources for this answer
- Carmustine Waymade 100 mg powder and solvent for concentrate for solution for infusion — Current selected SmPCemc · Summary of Product Characteristics
- Gliadel 7.7mg Implant — Current selected SmPCemc · Summary of Product Characteristics
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