Answer
Azarga is contraindicated in severe renal impairment (creatinine clearance below 30 ml/min) because brinzolamide and its main metabolite are predominantly excreted by the kidneys; Azarga has not been studied in these patients.
Sources for this answer
- Azarga 10mg/ml + 5mg/ml eye drops, suspensionNovartis Pharmaceuticals UK Ltd · emc · SmPC §4.2 Posology and method of administration · Version 13Document updated
Sources checked