Answer
Maraviroc only blocks HIV-1 that uses CCR5 to enter cells. It will not work adequately when CXCR4-using or dual/mixed-tropic virus is detectable.
Sources for this answer
- Maraviroc Waymade 150 mg — Current selected SmPCemc · Summary of Product Characteristics
- Celsentri 20 mg/ml oral solution — Current selected SmPCemc · Summary of Product Characteristics
- CELSENTRI 150 mg film-coated tablets — Current selected SmPC