Answer
Prednisone or prednisolone reduces the effects of excess mineralocorticoids caused by CYP17 inhibition, including high blood pressure, low potassium and fluid retention. It should not be stopped suddenly without specialist advice.
Sources for this answer
- Abiraterone 500mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance