Answer
It excludes intracranial bleeding because thrombolysis could worsen a haemorrhagic stroke.
Sources for this answer
- Metalyse 5 000 units (25 mg) powder for solution for injection — Current selected SmPCemc · Summary of Product Characteristics
- NHSNHS · NHS medicine guidance
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.