arsenic trioxide · Medicine question

Why does using amphotericin B with arsenic trioxide increase the risk of torsade de pointes?

Name: Why does using amphotericin B with arsenic trioxide increase the risk of torsade de pointes?
Published: 2026-11-08T01:36:42.521Z

iatroX medicinesPublished 8 November 2026

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Amphotericin B can cause hypokalaemia or hypomagnesaemia, which may increase torsade de pointes risk during arsenic trioxide (Trisenox) treatment, when QT/QTc prolongation is expected.

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Trisenox (arsenic trioxide) 2mg/ml Concentrate for Solution for InfusionTeva Pharma B.V. · emc · SmPC §4.5 Interaction with other medicinal products · Version 4Document updated 14 April 2026

Sources checked 8 November 2026

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