Answer
Gadobutrol is removed mainly through the kidneys. Severe impairment delays clearance and increases concern about the rare condition nephrogenic systemic fibrosis.
Sources for this answer
- Gadobutrol 1.0 mmol/ml solution for injection in prefilled syringe/cartridge' — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.