Answer
Levocetirizine is cleared mainly through the kidneys. Accumulation and adverse effects are more likely with reduced renal function, and dialysis-dependent end-stage renal disease is a contraindication.
Sources for this answer
- Levocetirizine 5 mg film-coated tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.