Answer
Cefoxitin is eliminated mainly unchanged by the kidneys. Reduced kidney function can keep it in the body much longer and increase adverse-effect risk, including neurological effects.
Sources for this answer
- Renoxitin 1g and 2g Powder for Solution for Injection or Infusion — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.