Answer
Combining Suprefact (buserelin acetate) injection with methadone requires careful evaluation because androgen deprivation may prolong the QT interval, and methadone is listed among medicines that prolong QT or can induce Torsade de pointes.
Sources for this answer
- Suprefact 1 mg/ml Injection solution for injectionNeon Healthcare Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
Sources checked