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Medicines leuprorelin acetateQuestion & answer

leuprorelin acetate · Medicine question

Why can symptoms briefly worsen?

iatroX medicinesMedicine guide reviewed 20 August 2026

The answer

Answer

The initial temporary testosterone rise, called tumour flare, may worsen bone pain, urinary obstruction or neurological symptoms.

Sources for this answer

Staladex 11.25mg Implant — Current selected SmPCemc · Summary of Product Characteristics
Prostap SR DCS — Current selected SmPCemc · Summary of Product Characteristics
NHS

NHS · NHS medicine guidance

General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.

The full medicine guide

leuprorelin acetate

Read the wider context, including uses, precautions and the sources behind this medicine guide.

Read the leuprorelin acetate guide

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