Answer
Paroxetine inhibits CYP2D6, an enzyme needed to convert tamoxifen into an important active metabolite. An alternative antidepressant may therefore be considered.
Sources for this answer
- Paroxetine 10 mg Tablets — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.